{
    "nodes": [
        [
            "Brugada Syndrome",
            "DISEASE"
        ],
        [
            "SCN5A",
            "GENE"
        ],
        [
            "SCN1B",
            "GENE"
        ],
        [
            "SCN10A",
            "GENE"
        ],
        [
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        ],
        [
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            "GENE"
        ]
    ],
    "edges": [
        [
            [
                "Brugada Syndrome",
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            11.965413,
            [
                [
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                    "36883079"
                ],
                [
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                    "35861988"
                ],
                [
                    "Gang Yu, Susmita Chakrabarti, Miroslava Tischenko, Ai-Lan Chen, Zhijie Wang, Hyosuk Cho, Brent A French, Sathyamangla V Naga Prasad, Qiuyun Chen, Qing K Wang (2022). Gene therapy targeting protein trafficking regulator MOG1 in mouse models of Brugada syndrome, arrhythmias, and mild cardiomyopathy. Science translational medicine, eabf3136. https://doi.org/10.1126/scitranslmed.abf3136 PMID: 35675436",
                    "35675436"
                ],
                [
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                    "33920294"
                ],
                [
                    "Zhong-He Zhang, Hector Barajas-Martínez, Hao Xia, Bian Li, John A Capra, Jerome Clatot, Gan-Xiao Chen, Xiu Chen, Bo Yang, Hong Jiang, Gary Tse, Yoshiyasu Aizawa, Michael H Gollob, Melvin Scheinman, Charles Antzelevitch, Dan Hu (2021). Distinct Features of Probands With Early Repolarization and Brugada Syndromes Carrying SCN5A Pathogenic Variants. Journal of the American College of Cardiology, 1603-1617. https://doi.org/10.1016/j.jacc.2021.08.024 PMID: 34649698",
                    "34649698"
                ],
                [
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                    "32818936"
                ],
                [
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                    "32709127"
                ],
                [
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                    "30517061"
                ],
                [
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                    "30776697"
                ],
                [
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                    "29593552"
                ]
            ]
        ],
        [
            [
                "Brugada Syndrome",
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            11.98171,
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                [
                    "Lu-Chen Weng, Shaan Khurshid, Amelia Weber Hall, Victor Nauffal, Valerie N Morrill, Yan V Sun, Joel T Rämö, Dominik Beer, Simon Lee, Girish Nadkarni, Renee Johnson, Laura Andreasen, Anne Clayton, Clive R Pullinger, Zachary T Yoneda, Daniel J Friedman, Matthew C Hyman, Renae L Judy, Allan C Skanes, Kate M Orland, Paloma Jordà, Timothy M Treu, Matthew T Oetjens, Rajesh Subbiah, Jacob P Hartmann, Heidi T May, John P Kane, Tariq Z Issa, Navid A Nafissi, Peter Leong-Sit, Marie-Pierre Dubé, Carolina Roselli, Seung Hoan Choi,  , Jean-Claude Tardif, Habib R Khan, Stacey Knight, Jesper H Svendsen, Bruce Walker, Richard Karlsson Linnér, J Michael Gaziano, Rafik Tadros, Diane Fatkin, Daniel J Rader, Svati H Shah, Dan M Roden, Gregory M Marcus, Ruth J F Loos, Scott M Damrauer, Christopher M Haggerty, Kelly Cho, Aarno Palotie, Morten S Olesen, Lee L Eckhardt, Jason D Roberts, Michael J Cutler, M Benjamin Shoemaker, Peter W F Wilson, Patrick T Ellinor, Steven A Lubitz (2024). Meta-Analysis of Genome-Wide Association Studies Reveals Genetic Mechanisms of Supraventricular Arrhythmias. Circulation. Genomic and precision medicine, e004320. https://doi.org/10.1161/CIRCGEN.123.004320 PMID: 38804128",
                    "38804128"
                ],
                [
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                    "36764349"
                ],
                [
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                    "37373335"
                ],
                [
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                ],
                [
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                ],
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                ],
                [
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                    "33910361"
                ],
                [
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                    "33202810"
                ],
                [
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                    "32948286"
                ],
                [
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                    "32619740"
                ]
            ]
        ],
        [
            [
                "Brugada Syndrome",
                "CACNA1C"
            ],
            11.981665000000001,
            [
                [
                    "Lorenzo Cipriano, Raffaele Piscopo, Chiara Aiello, Antonio Novelli, Achille Iolascon, Carmelo Piscopo (2024). Expanding the Phenotype of the CACNA1C-Associated Neurological Disorders in Children: Systematic Literature Review and Description of a Novel Mutation. Children (Basel, Switzerland). https://doi.org/10.3390/children11050541 PMID: 38790536",
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                ],
                [
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                ],
                [
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                [
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                ],
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                ],
                [
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                ]
            ]
        ],
        [
            [
                "Brugada Syndrome",
                "SCN5A"
            ],
            14.260516,
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                ],
                [
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                ]
            ]
        ],
        [
            [
                "Brugada Syndrome",
                "SCN1B"
            ],
            11.9905975,
            [
                [
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                ]
            ]
        ]
    ]
}